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P0300 on Gmc Yukon

Random/Multiple Cylinder Misfire Detected

NHTSA Reports
3
Severity
medium
Most Affected
2020, 2021, 2025
Crashes / Fires
0 / 0
Source: NHTSA Complaints Database · SAE J2012
Last reviewed: Last updated:

Methodology: Reviewed against the SAE J2012 generic DTC definition and NHTSA owner-complaint patterns, then scoped to Gmc Yukon context without treating complaints as confirmed diagnoses.

Sources: SAE/OBD-II definitions, manufacturer service information, and public reliability reports (including NHTSA where applicable).

Limits: Guidance is informational and may not match every model-year or revision. Confirm with the official manual and diagnostics before replacing parts. For safety-critical or electrical work, use a qualified technician.

What P0300 Means on Your Gmc Yukon

P0300 is a diagnostic trouble code indicating: Random/Multiple Cylinder Misfire Detected. This code relates to the ignition system system. The vehicle's computer detected a condition outside normal operating parameters and stored this code.

3 GMC YUKON owners have reported this issue to NHTSA across model years 2020-2025. Most reports come from the 2020, 2021 model years.

Real Gmc Yukon Owner Reports

Source: NHTSA Complaints Database

"I purchased a new 2020 GMC Yukon in May of 2020. Between May 2020 and November 2025 the vehicle was routinely serviced on or before the due date recommend by the manufacturer."

— 2020 Gmc Yukon owner · ENGINE · Filed 2025-11-04

"I got 3 messages on the dash going off simultaneously 1. Service Traction Control System 2. Forward Collision System unavailable 3."

— 2021 Gmc Yukon owner · ENGINE,FUEL/PROPULSION SYSTEM · Filed 2025-11-22

"While driving on a highway, the vehicle intermittently suffers a sudden loss of engine power during acceleration, accompanied by a flashing check engine light."

— 2025 Gmc Yukon owner · POWER TRAIN,ENGINE · Filed 2025-10-25

All reports filed by vehicle owners directly with the U.S. Department of Transportation.

📊 Complaint Trend by Model Year

1
'20
1
'21
1
'25

Common Causes on Gmc Yukon

Based on NHTSA complaint component analysis for this vehicle.

ENGINE 33.3%
ENGINE,FUEL/PROPULSION SYSTEM 33.3%
POWER TRAIN,ENGINE 33.3%

What To Do Next

  1. 1
    Check for recalls on YOUR VIN

    Go to nhtsa.gov/recalls and enter your VIN. If your vehicle is covered, repairs are free.

  2. 2
    Get a proper diagnosis

    A code alone doesn't tell you the exact failed part. A diagnostic at a shop ($50–$150) pinpoints the root cause before you spend money on parts.

  3. 3
    Compare repair quotes

    Get 2–3 quotes. Dealer vs. independent shop prices often differ 30–50% for the same repair.

Frequently Asked Questions

P0300 on Other Vehicles