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P0300 on CHRYSLER 300

Random/Multiple Cylinder Misfire Detected

NHTSA Reports
4
Severity
medium
Most Affected
2006, 2011
Crashes / Fires
0 / 0
Source: NHTSA Complaints Database · SAE J2012
Last reviewed: Last updated:

Methodology: Reviewed against the SAE J2012 generic DTC definition and NHTSA owner-complaint patterns, then scoped to Chrysler 300 context without treating complaints as confirmed diagnoses.

Sources: SAE/OBD-II definitions, manufacturer service information, and public reliability reports (including NHTSA where applicable).

Limits: Guidance is informational and may not match every model-year or revision. Confirm with the official manual and diagnostics before replacing parts. For safety-critical or electrical work, use a qualified technician.

What P0300 Means on Your CHRYSLER 300

P0300 is a diagnostic trouble code indicating: Random/Multiple Cylinder Misfire Detected. This code relates to the ignition system. The vehicle's computer detected a condition outside normal operating parameters and stored this code.

4 CHRYSLER 300 owners have reported this issue to NHTSA across model years 2006, 2011. The most commonly reported component is Engine And Engine Cooling.

Real CHRYSLER 300 Owner Reports

Source: NHTSA Complaints Database

"My chrysler 300c hemi started idling rough and showing code p0300. oil/plugs were changed, and my car worked well for ~500 miles. after which the low oil level light chimmed. after taking to the dealer the oil pressure switch was replaced and all was right."

— 2006 CHRYSLER 300 owner · FUEL SYSTEM, GASOLINE,VEHICLE SPEED CONTROL,ENGINE · Filed 03/20/2014

"Check engine light has appeared on an average of 1 time per month since purchase of the vehicle 8/4/07. repeated visits to dealership gegnas chrysler in philadelphia pa has not corrected issue to date."

— 2006 CHRYSLER 300 owner · ENGINE AND ENGINE COOLING · Filed 03/30/2009

"Code p0300 random misfire code at mileage 32161 code p0300 random misfire code at mileage 32217 continuous periodic misfirings in engine not resolved code p0300 random misfire code at mileage 66962 code p0300 random misfire code at mileage 70762 code p00132-02 sensor failure at mileage 71146 s"

— 2006 CHRYSLER 300 owner · ENGINE AND ENGINE COOLING · Filed 01/20/2009

"Camshaft / lifters are prematurely wearing out( wiped ) the car is throwing a p0300 ,p0303 code but the spark plugs,coils etc are fine .."

— 2011 CHRYSLER 300 owner · UNKNOWN OR OTHER,ENGINE · Filed 09/02/2019

All reports filed by vehicle owners directly with the U.S. Department of Transportation.

📊 Complaint Trend by Model Year

3
'06
1
'11

Common Causes on CHRYSLER 300

Based on NHTSA complaint component analysis for this vehicle.

ENGINE and ENGINE COOLING 50%
FUEL SYSTEM, GASOLINE,VEHICLE SPEED CONTROL,ENGINE 25%
UNKNOWN or OTHER,ENGINE 25%

What To Do Next

  1. 1
    Check for recalls on YOUR VIN

    Go to nhtsa.gov/recalls and enter your VIN. If your vehicle is covered, repairs are free.

  2. 2
    Get a proper diagnosis

    A code alone doesn't tell you the exact failed part. A diagnostic at a shop ($50–$150) pinpoints the root cause before you spend money on parts.

  3. 3
    Compare repair quotes

    Get 2–3 quotes. Dealer vs. independent shop prices often differ 30–50% for the same repair.

Frequently Asked Questions

P0300 on Other Vehicles