P0301 on Toyota Highlander
Cylinder 1 Misfire Detected
Methodology: Reviewed against the SAE J2012 generic DTC definition and NHTSA owner-complaint patterns, then scoped to Toyota Highlander context without treating complaints as confirmed diagnoses.
Sources: SAE/OBD-II definitions, manufacturer service information, and public reliability reports (including NHTSA where applicable).
- SAE J2012 Diagnostic Trouble Code Definitions — Generic diagnostic trouble code definition reference for P0301.
- NHTSA recalls, complaints, and manufacturer communications — Used to check public owner complaint context, recall status, and safety-related manufacturer communications by VIN or vehicle.
Limits: Guidance is informational and may not match every model-year or revision. Confirm with the official manual and diagnostics before replacing parts. For safety-critical or electrical work, use a qualified technician.
What P0301 Means on Your Toyota Highlander
P0301 is a diagnostic trouble code indicating: Cylinder 1 Misfire Detected. This code relates to the ignition system system. The vehicle's computer detected a condition outside normal operating parameters and stored this code.
Real Toyota Highlander Owner Reports
Source: NHTSA Complaints Database
"1. The 3.5L V6 Engine (2GR-FE) failed due to the subsequent loss of lubrication caused by the rupture of the Oil Cooler Pipe (Rubber component), a manufacturing defect known under TSB T-SB-0201-11 (ZE2 Program)."
"I experienced a sudden engine failure while driving my 2015 Toyota Highlander on Interstate 294 outside Chicago. I was driving about 75 mph in the far left lane."
All reports filed by vehicle owners directly with the U.S. Department of Transportation.
📊 Complaint Trend by Model Year
Common Causes on Toyota Highlander
Based on NHTSA complaint component analysis for this vehicle.
What To Do Next
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1
Check for recalls on YOUR VIN
Go to nhtsa.gov/recalls and enter your VIN. If your vehicle is covered, repairs are free.
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2
Get a proper diagnosis
A code alone doesn't tell you the exact failed part. A diagnostic at a shop ($50–$150) pinpoints the root cause before you spend money on parts.
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3
Compare repair quotes
Get 2–3 quotes. Dealer vs. independent shop prices often differ 30–50% for the same repair.